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Postdoctoral Positions

Why come to CSHL for your Postdoc?

CSHL has long been recognized as a place for nurturing young scientists, with postdoctoral researchers being integral parts of the discovery process. CSHL’s relatively small size—around 55 labs—combined with its collaborative and multidisciplinary research programs creates a unique environment for the next step in your scientific career.

Current Open Postdoc Positions

Breast Cancer researchers at CSHL

Scientific excellence

CSHL is one of the leading biomedical research institutions in the U.S., with research in five main areas: cancer biology, neuroscience, plant biology, quantitative biology, and genomics. In addition, CSHL is an NCI Cancer Center dedicated to studying the fundamental biology of human cancer, and translating these breakthroughs from bench to bedside. Across the entire community at CSHL, there is a distinct spirit of scientific pursuit and interactions, resulting in innovative and productive collaborations.

light-sheet microscopy

Resources

CSHL’s postdocs have access to all the scientific resources available on campus. This includes Core Facilities that feature the latest technology and expertise. These Cores are fast, reliable, and cost-effective, offering in-house support that can be customized and collaborative to spur the development of novel technological applications and creative research.

Career development

Your training as a postdoc at CSHL extends beyond the bench. There is a suite of Career Development offerings, including short courses, workshops, lectures, and seminars that provide opportunities for scientific enrichment and professional development. In addition, there are programs in career exploration and opportunities to develop skills such as leadership, mentoring and communication.

photo of CSHL Meetings & Courses

Extramural meetings & courses

CSHL’s extensive brings top scientists from around the world to campus to present and discuss the latest research in a wide variety of scientific. This is great opportunity to network and meet with colleagues.

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A vibrant community

The Laboratory offers a collegial and collaborative work environment as well as a beautiful location just a short train ride from New York City. CSHL has several postdoctoral and student-led groups, including an active Postdoctoral Liaison Committee (PDLC), whose purpose is to represent the interests of and advocate for the CSHL postdoctoral community.

photo of the exterior CSHL Day Care Center building
Image: Jeff Goldberg/ESTO

Onsite child care center

CSHL has an excellent and affordable, licensed, on-site childcare center that serves children from six weeks to six years old.

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Compensation & benefits

CSHL offers an excellent comprehensive benefits program, an onsite Wellness Center, a Fitness Center, subsidized dining experiences and complimentary shuttle service. The CSHL Housing Office can help postdocs find affordable housing, either through a shared-housing program, or through local realtors. In addition, all postdoctoral fellows are eligible for relocation reimbursement and a family allowance. The Postdoctoral Fellows are compensated based on their years of experience. The salaries can be accessed at “Postdoctoral Stipend Schedule.” (PDF)

Postdoctoral Fellow opportunities

– – 00399

Our lab is interested in how the brain accomplishes the ongoing transformation from sensation to action during natural behaviors. Vocal communication is ideally suited to study natural and flexible sensorimotor transformations. During a conversation, our brain must interpret what we hear and control our vocal response. Recently, we have discovered that a neo-tropical rodent, Alston’s singing mouse, engages in fast vocal interactions, even under laboratory settings.

– – 00888

Our lab is interested in how the brain accomplishes the ongoing transformation from sensation to action during natural behaviors. Vocal communication is ideally suited to study natural and flexible sensorimotor transformations. During a conversation, our brain must interpret what we hear and control our vocal response. Recently, we have discovered that a neo-tropical rodent, Alston’s singing mouse, engages in fast vocal interactions, even under laboratory settings.

– – 807

The Furukawa Laboratory is actively seeking a postdoctoral researcher. We explore the molecular underpinnings of neurotransmission, neuroplasticity, and neuron-targeted autoimmunity triggered by cancer. We employ a multidisciplinary approach, integrating structural biology, high-resolution imaging, and electrophysiology. While expertise in cryo-electron tomography (cryo-ET), single-particle cryo-electron microscopy (cryo-EM), x-ray crystallography, patch-clamp, slice electrophysiology, or molecular neuroscience is advantageous, it is not a prerequisite for application.

– Gholami Lab – 00303

A position is available for a postdoctoral researcher with a strong background in cancer biology and immunology. This postdoctoral fellow will work under the direction of Dr. Gholami, an Associate Professor and surgeon-scientist at Northwell Health and ư, within the laboratory of Dr. Westcott. The Gholami laboratory research is centered on understanding the host-immune cell interactions and the mechanisms by which the immune system and tumor microenvironment play a role in the biology and anti-tumor response of liver metastases. More specifically, the laboratory research focuses on mechanisms of immune resistance in liver metastases to develop novel immune augmenting therapies and practice-changing clinical trials.

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We are currently seeking a Postdoctoral Fellow in the laboratory of Dr. Helen Hou at ư (), starting in Fall 2023 or Spring 2024. You will play a decisive role in the research program of an interdisciplinary lab with the latest technologies in neuroscience, studying how the brain controls movements and natural behaviors, including but not limited to how the brain coordinates muscles of facial expressions to convey internal states.

– , , Lukey Lab – 03167-R

Together, the Borniger, Lukey, and Janowitz laboratory at ư (CSHL) offer a unique opportunity for a highly motivated and creative postdoctoral researcher, with strong experimental and analytical skills, to investigate the reciprocal interaction of sleep and cancer progression. You will become part of a multidisciplinary team of basic researchers and clinicians studying tumor-host interactions, using integrative techniques from neuroscience, endocrinology, metabolomics, and immunology to dissect the mechanisms connecting sleep disruption with aberrant metabolic and immune responses during cancer progression.

– – 00583

Associate Professor Justin B. Kinney seeks a postdoctoral fellow to carry out experimental and/or computational work aimed at understanding how genomic sequence quantitatively controls alternative mRNA splicing in humans. Research pursued by the postdoctoral fellow will likely involve the use of massively parallel reporter assays (MPRAs) and/or the development of deep neural network models.
The Kinney Lab develops experimental, computational, and mathematical approaches for deciphering the quantitative molecular mechanisms of gene regulation. Their experimental work centers on the use of MPRAs, a technology that Dr. Kinney and his lab have pioneered and continue to advance. They also develop machine learning approaches, including deep learning strategies, for extracting quantitative models of sequence-function relationships from MPRA datasets and for interpreting these models in terms of underlying biophysical mechanisms.

Koulakov Lab – 03057-R

ư is looking for outstanding candidates to fill postdoctoral positions in theoretical neuroscience. The position is open under specific projects as well as general research involving the application of methods from theoretical physics, mathematics, and machine learning with the goal to understand the brain function.

L.Zhang Lab – 03248-R

Dr. Lingbo Zhang’s Laboratory at ư (CSHL) is part of a $75 million Center for Therapeutics Research at CSHL. There are multiple fully funded postdoctoral fellowships available in the Zhang Laboratory to investigate roles of nervous system activities and micronutrients in regulating hematologic cancers and to develop novel therapeutic strategies for these diseases.

Tonks Lab – 03137-R

Protein Tyrosine Phosphatases and the Regulation of Cell Signaling: from Basic Research to New Therapeutics. The protein phosphatases are critical, specific regulators of signaling that serve an essential function, in a coordinated manner with the protein kinases, to determine the response to a physiological stimulus. The Tonks Lab takes a multidisciplinary approach to study the structure, regulation and function of the protein tyrosine phosphatase (PTP) family of enzymes, to illustrate their fundamental importance to the control of signal transduction under normal and pathophysiological conditions. As functional studies have established links to disease, the PTPs have been garnering attention as potential therapeutic targets; however, they remain a largely untapped resource for drug development.

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The Trotman Lab at ư is seeking applications for postdoctoral candidates with a strong background in neurobiology. We study lethal metastatic cancer. The project aims to define how peripheral nerves in the metastatic tumor environment interacti with cancer cells and affect progression, therapy and disease outcome.

– – 00737

The laboratory of Dr. Christopher Vakoc at ư seeks to hire a Postdoctoral Fellow to lead a project focused on cancer epigenetics and lineage plasticity. The key requirement for this position is recent Ph.D. training in cancer biology, cell biology, molecular genetics, or epigenetics. Familiarity with cancer models (tissue culture and/or animal), CRISPR-based genetic perturbations, and genome-scale evaluations of chromatin would be the most relevant for this position, however exceptional candidates will be considered with any area of biological research expertise. Candidates from non-traditional and/or under-represented backgrounds are strongly encouraged to apply.

Van Aelst Lab – 02796-R

The main focus of research will be to study the roles of genes associated with human diseases in the development and function of neural circuits, using molecular, genetic and viral engineering, optogenetics, imaging, electrophysiology, and behavior analysis.

Van Aelst Lab & Lukey Lab – 609

We are looking for candidates who will develop their own research questions in line with the overarching goals of this project. Numerous resources will be available, including state-of-the-art laboratory space and the opportunity to discuss science in a diverse and supportive environment. This project also provides opportunities to develop skills in the application of murine glioma models, metabolomics, and advanced microscopy.

Westcott Laboratory – 00681

The Westcott Laboratory at ư is seeking applications for postdoctoral candidates to carry our experimental and/or computational work aimed at understanding how cancer coevolves with the immune system in mouse models and clinical colorectal cancer specimens. The research program will involve modeling cancer clonal evolution under different immunogenic contexts in powerful new mouse models we have developed, and will incorporate cutting-edge techniques in multiomics and spatial biology, for which the lab has recently obtained funding.

– – 02822-R

The Wigler and Levy research group are seeking a Computational Post Doc that will have a key role in a multi-disciplinary team of wet-bench and computational researchers working to revolutionize cancer detection and treatment by developing novel genomic technologies. We are re-envisioning the tools of genetics research by coupling innovation at the bench with novel computational methods. We have developed methods for inexpensive copy number (SMASH), generating long reads from short-read sequencers (muSeq), encapsulation of cells in acrylamide gel (BAG-seq), sensitive detection of cancer genomes (MASQ), and most recently mutational sequencing for short tandem repeats (muSTR). Applicants may review our most recent publications at .

– – 02869-R

A Postdoc Fellow position is available at The at CSHL Cancer Center. We are recruiting new members passionate about drug discovery and chemical biology. Our lab is working to understand the molecular mechanisms leading to efficient elicitation of tumor vulnerability for potent cancer targeting. We develop Targeted Protein Degradation (TPD) therapeutic strategies to abrogate or rewire cancer cell signaling. We have recently established a new discovery platform to expand the landscape of TPD E3 ligases and targeting modalities beyond conventional small molecules (Genes & Development (2022) 36:1031-1042.; Genes & Development (2023) 37: 1-17). For this open position, the project direction will be focused on continuing developing and validating novel TPD molecules to target undruggable proteins.